Root bark and occasionally trunk and fruits. Fruit juice is also used.
Formerly the decoction of root bark was used as a purgative to cause tapeworm expulsion. It has now been deprecated in human therapy, being only used in veterinary medicine.
Popularly, the pulp of the fruit has been used to make grenadine syrup to combat sore throats. Furthermore, the notable tannin content throughout the plant has been used as an astringent and antidiarrheal.
The root bark and trunk have anthelmintic properties, especially against tapeworms. The rind of the fruit is astringent and antibacterial, while the fruits have antioxidant properties due to their hydrolyzable tannins.
Some components of the extract show antibacterial and antifungal effects.
The juice obtained from both the arils of the seeds and the whole fruit have shown strong antioxidant effects. The polyphenols of pomegranate juice inhibit the oxidation of low molecular weight lipoproteins (LDL, popularly known as “bad cholesterol”).
Animal experimentation has revealed that the juice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and the development of atherosclerosis, effects attributed to its inhibitory action on oxidative stress.